منابع مشابه
Kindling in alcohol withdrawal.
In many alcoholics, the severity of withdrawal symptoms increases after repeated withdrawal episodes. This exacerbation may be attributable to a kindling process. Kindling is a phenomenon in which a weak electrical or chemical stimulus, which initially causes no overt behavioral responses, results in the appearance of behavioral effects, such as seizures, when it is administered repeatedly. Bot...
متن کاملInhibitory effects of succinic acid on chemical kindling and amygdala electrical kindling in rats.
AIM To investigate the effects and mechanism of succinic acid on pentylenetetrazol (PTZ) chemical kindling and amygdala electrical kindling in rats. METHODS PTZ chemical kindling and amygdala electrical kindling models were established in rats. The effects of succinic acid on the behavior and afterdischarge of kindled rats were observed. The mice were pretreated with succinic acid, 30 min lat...
متن کاملDoes Conditioning Contribute to Kindling? 1 Does Inadvertent Conditioning Contribute to the Major Features of Kindling?
Conventional kindling experiments appear ideal for generating inadvertent conditioned effects: A variety of stimuli (e.g., removal from the home cage, attachment to the stimulation lead, and placement in the stimulation environment) are repeatedly presented to the animal prior to each stimulation and convulsion. We recently demonstrated that the stimulation environment can have a major impact o...
متن کاملEffects of Omega-3 Fatty Acids on Pentylenetetrazole-induced Kindling, Cognitive Impairment and Oxidative Stress
Epilepsy as well as chronic use of most antiepileptic drugs, particularly in children, predisposes to cognitive impairment. The brain is considered abnormally sensitive to oxidative stress and damage which observed during seizure activity. Omega-3 (OM3) fatty acids are known antioxidants that play a role in nervous system activity, cognitive development, memory-related learning, and synaptic tr...
متن کاملDiversity of kindling effects: EEG manifestations in cats during kindling in the hippocampal formation.
The formation and subsequent development of after-discharges (ADs) and spontaneous interictal spikes was investigated in a group of ten kindled cats. The electrodes used for electrical stimulation and EEG recording were located in various parts of the hippocampal formation: in the hippocampal gyrus, dentate gyrus, subiculum and entorhinal cortex. The animals were stimulated once daily with 1 s ...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1987
ISSN: 0022-3050
DOI: 10.1136/jnnp.50.5.651-b